This lecture gives optometrists a practical framework for interpreting dermatopathology biopsy reports in periocular and adnexal eye care. It emphasizes correlating clinical lesion features with normal skin histology and common nondiagnostic histologic patterns. Using case-based examples, participants review key clinical descriptors, normal skin histology, and foundational terms such as acanthosis, hyperkeratosis, parakeratosis, actinic keratosis, cutaneous horn, and solar elastosis. The course supports informed management decisions, recognition of concerning or incomplete findings, and appropriate next steps.