A multitude of studies globally have now documented shifts in the distribution of marine fishes and fisheries in relation to changing ocean conditions. These shifts may impact fisheries productivity by altering the distribution, growth, and sexual maturity of fish, while also changing species targeted by the fisheries. These changes can present opportunities as well as challenges to fisheries management. The proposed research will use data from long-term monitoring programs to model historical, contemporary, and future trends in the targeting, distribution, growth, and sexual maturity of select fish and fisheries along the extensive latitudinal gradient of Florida’s west coast; contemporary distributions of fisheries species will also be monitored using sentinel sites along the coastal gradient. A suite of environmental variables related to changing ocean conditions will be considered as forcing factors (e.g., temperature, dissolved oxygen, salinity), along with other potentially important variables, such as changes in habitat and prey availability. We will also solicit fishers’ knowledge of changes over time to understand and integrate their experiences. Co-production activities involving natural resource managers and local knowledge of fishers will be used to identify priority species for modeling. Expected findings include northward shifts in the centers of distribution of many fish species, and potentially offshore to deeper, cooler water, along with changes in species targeted through time. Shifting distributions present a unique challenge to the expanding application of regional approaches to fisheries management, as would changes in size at sexual maturity that are reflected in minimum length limit regulations. This research, in tandem with co-production involving fishers, natural resource managers, and fisheries agencies, will ultimately lead to adaptive, future management of recreational and commercial fisheries important to coastal fishing communities.